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Welcome

Motivated by diseases arising from the misregulation of proteins and nucleic acids, our biophysical approach makes connections between molecular mechanism and cellular function through time-resolved spectral imaging at multiple scales, from in vitro to single cell to whole organism.

We are part of the Chemistry Department at Yale University.

Recent Publications

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H.B. Castillo*, S.O. Shuster*, L.H. Tarekegn, and C.M. Davis

Oleic acid differentially affects lipid droplet storage of de novo synthesized lipids in hepatocytes and adipocytes

Chem. Comm. 2024, accepted.

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E. Knab and C.M. Davis

Chemical interactions modulate lambda 6-85 stability in cells

Protein Sci. 2023, 32 (7), e4698.

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S.O. Shuster, M.J. Burke, and C.M. Davis       

Spatiotemporal heterogeneity of de novo lipogenesis in fixed and living single cells

J. Phys. Chem. B 2023, 127 (13), 2918-2926.

Current and Past Funding Sources

We acknowledge the funding agencies that made this work possible

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