top of page
Figure1v3.png

Welcome

Motivated by diseases arising from the misregulation of proteins and nucleic acids, our biophysical approach makes connections between molecular mechanism and cellular function through time-resolved spectral imaging at multiple scales, from in vitro to single cell to whole organism.

​

We are part of the Chemistry Department at Yale University.

Recent Publications

PA_TOC.tif

H.B. Castillo, C.M. Davis

Optical photothermal infrared imaging of fatty acid esterification in the ER of living cells

Sci. Adv. 2026, 12 (28) eaed6477.

​

Review.tiff

E. Knab, U. Tahir and C.M. Davis       

Mimetics of in-cell and subcellular crowding and solvation for protein folding

Biochem. Soc. Trans.  2026, 54 (4), 413-425.

barnase.png

U. Tahir and C.M. Davis

Weak, specific chemical interactions dictate barnase stability in diverse cellular environments

Protein Sci. 2025, 34 (5), e70128.

​

Current and Past Funding Sources

We acknowledge the funding agencies that made this work possible

CCF.png
RCSA_edited.jpg
liver center.png
Gordon_and_Betty_Moore_Foundation_logo_e
NIH_Logo_165.gif
nsf1.jpg
Hevolution AFAR.png
yale-blue_2x.png
  • Twitter Clean Grey

© 2019 Davis Lab

Davis Lab, Yale University

Department of Chemistry

255 Prospect St, KCL 108

New Haven, CT 06511

bottom of page